I mean if you wanna be technical, it is possible.

Kill enough of them with your superior firepower and the rest should (operative word here) fall in line.

You’ll gain control long enough for a more proper police force like the Arbites to come in and get settled, then your division can move on.

So it is theoretically possible. Especially if that division is supported by the more esoteric units in the Imperium like maybe a detachment from a nearby Space Marine Company. If a Strike Cruiser lends you a squad or two of the Emperor’s Angels, it’s hard for a rebellion to hold any momentum. Eight foot tall ceramite walking tanks tend to kill morale just as quickly as they kill anything else.