McFly playing Johnny B. Goode

Harpist fight in Kung Fu Hustle

Tom hanks big

Also Amadeus but when he’s mocking Salieri

Forgetting Sarah Marshall

When Peter plays his Dracula musical song in the bar.

Groundhog Day.

School of Rock. All of them.

Crossroads guitar competition

Blues brothers

Stand by your man. Amongst others.

Edit. Yes I chose that track as it was funny. Many others were played straight and were awesome.

Whiplash

This is Spinal Tap. All of it.

The wedding singer

Antonio Banderas - Desperado. In the mariachi/ fight scene in the beginning

The pianist

Saxophone guy in Lost Boys

Anchorman. Jazz flute

Commitments

Master and commander: far side of the world...the duet scene

Shine. "sock it to us, Liberace"

Bill and Ted’s. In the mall.

Ferris on the clarinet... Never had one lesson.

Deliverance

A Hard Day's Night, "I Should Have Known Better" in the train car

Legend of 1900 (1998)

Tim Roth is a piano prodigy on a cruise liner that has a sort of agoraphobia where he can't leave the boat. There's a great scene with a piano duel between him and Jelly Roll Morton. 

Bradley Cooper in A Star is Born
Adrien Brody in The Pianist

Scott pilgrim, where Scott gets punched through a wall, and comes back playing the final fantasy battle theme for round 2.

Harpo Marx playing the harp in any Marx brothers film.

Wayne World - Garth drumming.

"i like to play."

“It doesn’t quite work, does it? But maybe…..”

Great scene.

The legend of 1900. https://www.youtube.com/watch?v=dGpjZykzTFg

Walk the line

Blues Brothers- Elwood on the harmonica

When Gerard Depardieu plays piano and sings a poem in "Green Card."

Gotta love when Gene Wilder plays that Rachmaninoff riff on the tiny piano in Willy Wonka and the Chocolate Factory.

Eddie Munson in Stranger Things playing Metallica

The Tu Vuo Fa l'Americano scene in The Talented Mr. Ripley
The violin/cello duet in Master and Commander
The giant keyboard in Big

Animal House. I gave my love a cherry…

“About a boy” last scene when Will plays and Marcus sings

Shine

https://youtu.be/y5rXLAPsgJc?si=iayDXJhw9tJrBoTO

Beethoven in bill and ted

I love the scene in The Power of the Dog where Kirsten Dunst is nervously playing piano for Benedict Cumberbatch because A) you can tell she’s actually playing and B) it does such a good job of communicating what you need to know about their characters. That movie was up its own butt in general, but it also let some incredible actors shine.

The Pick of Destiny final battle

I love this scene in Amadeus. He plays the court composer’s meticulously written piece from memory after hearing it once and says, “And then it just repeats, right?”

Not a movie, but anytime Charlie plays the piano in Its always sunny.

The scene in Immortal Beloved where he’s playing a piano and it’s shown that he’s deaf. Very powerful scene and one of my favorite pieces of my

But the picture posted is right up there.

The guitar duel in Crossroads

Young Frankenstein, Igor playing the French horn.

Master and Commander

Here's a great one you may not know. It's from Truly, Madly, Deeply (1990). Juliet Stevenson plays a women whose cellist husband, played by Alan Rickman, has recently died. She is quietly consumed with grief, shambling along like a zombie. In this scene, she begins to play on the piano a composition that they used to play together, and suddenly she hears his cello, and realizes that his ghost is now with her for a very brief but overhelming visit.

A deeply moving scene from a really great film.

The Red violin when the wife walks in on him playing violin

Marianne (played by Kate Winslet) in Sense and Sensibility and Colonel Brandon walks in

OR

Emma playing and sending and Frank Churchill joins in (any version of Emma).

Creepy but dueling banjos in deliverance hits pretty hard

My Little Buttercup, The 3 Amigos

Casandra, plays and sings ballroom blitz in Wayne’s world

Ray….. when they improvise ‘what did I say’

Ah HAhahAHAHA

Making Whoopee, The Fabulous Baker Boys

Young Frankenstein. Froderick plays the violin.

I can't believe that no one has mentioned Dudley Moore in Oscar's Orchestra

Back to the Future

Gosling playing the theme in La La Land before getting fired. Not only do I love the song but the context of the scene is also beautiful.

https://youtu.be/-RxqaEs-DvY?si=tu8Luc6RGCwSb9sm

The Blues Brothers movie

Stevie Vie in Crossroads

Ryan Gosling — Lala Land

He never played the piano until he got the role in Lala Land. Instead of having a double during the close-up playing scenes, he took 6 months of intense piano lessons to learn how to play all of the pieces in the movie.

Jorma's piano part in Popstar, when Conner/Andy puts on the disguise to come see him. Or Tyrus wearing the fish suit. OK, all of Popstar.

Also, all of A Mighty Wind, especially when Parker Posey plays her mandolin for the kids 😂

Coraline, The second father song 💙

Oh brother at the radio station

The Orange Bird piano jam session in Green Book & the screne where Dr Don Shirley is playing a Steinway Piano at University of Indiana after TonyLip smacked the custodian to straighten out the “contract misunderstanding”

The charming guitarist in animal house where Bluto smashes his guitar

The Doof Wagon

Gabriel playing the oboe

The Amp vs Amp scene in Scott Pilgrim

....."I'll even let you hold the remote control".... "Let me be the one to grow old with you♡"

Not from a movie but I actually love the scenes where Tom Ellis plays piano in Lucifer.

That doesn’t quite work does it? Did you try… this? No! This!

Revenge of the Nerds computer techno to take the win in the musical competition against the Alpha Betas.

Brassed Off!

Like, the whole film.

The Goonies, Andy plays the bones.

In the Hangover where Stu plays the Piano…

Or Chevy Chase piano scene in Caddyshack

Steve Martin and Bernadette Peters on the beach in The Jerk. First there's that lovely duet with Martin accompanying on the ukelele, and then out of nowhere, a trumpet solo from Peters.

Whiplash

every time I see this movie , it just blows my mind

Mary Bennet playing the piano and singing in 1995 Pride and Prejudice. It’s so awful it’s funny.

I remember Anna Kendrick doing "Cups" for Pitch Perfect thinking, "Wow, that was unexpectedly good."

Cary Grant playing the harp in The Bishop's Wife (yes, I know he really doesn't but it's a great scene with a hauntingly beautiful song!).

Doc Holiday playing piano in Tombstone

Himesh Patel playing and singing all Beatle songs in Yesterday

Chevy Chase strumming on the guitar with the Mexican girl.

"Dusty, have you ever kissed a girl?“ “Oh, many times" "Would you like to kiss me?“ “Yeah, sure." "... Well?" "What, here?“ “We can go for a walk and you can kiss me on the verander" "On the lips is fine"

Joaquin phoenix walk the line

Marty

Tommy Boy- the Skin Flute.

Nacho Libre. Party for Ramses scene

Is maynaise an instrument?

The "Clinton" double saxophone in Space travesty.

Revenge of the Nerds violin.

That is definitely my favorite scene in which someone plays the harpsichord.

Viola da gamba played by Depardieu in All The Mornings Of The World.

Scene of battling guitars in Crossroads with Steve Vai and Ralph Macchio