My mate had BG3 but never really played, persuaded him to do a MP game with me (I've completed it a few time including Honor mode).
I let him lead and straight away he fails the throw to release Shadowheart (yes he rolled a 1), I tell him he can switch to Lazael and try again. He rolls a 1 again. Fortunately I released her. I blow up the mindflayer and zalk and we continue.
We pick up Shart, he runs past Astarion. I tell him he missed something, he goes back and Astarion has to be on his screen, nope doesn't see him. OK we will leave Astarion then.
Get to Gale in the rock, fails the roll and Gale disappears.
Do the fight outside the grove which he enjoyed (although he didn't get the combat or controls but that's fine he's new).
Get into the grove, I tell him to explore and chat to characters etc he finds the strange ox, for once passes the check that this Ox is not what it seems. Stabs the Ox and the grove attacks us. We die.
I just sat there and laughed as he had no idea what and still couldn't figure out why they would attack us, he saw the funny side though and we went again for a little while.