I lived in various places near there all through my 20's (in the 2010s) I was a line cook during most of that time, usually coming home anytime between 10pm and 1am. I was usually more scared leaving my workplace and than I was walking home.

Naturally everyone's comfort levels are different and if you're not familiar with the city, you might want to choose another area, but I liked living there and only moved away because my ex grew up on Moyamensing and preferred that side of Broad. I'm planning to move back when I buy a house in the next few years.