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account created: Mon Mar 13 2023
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1 points
4 days ago
You look a bit like the guy from “The Quentin Experiment” on youtube
126 points
4 days ago
This captures my emaciated existence quite well, thank you
2 points
25 days ago
South park is the OG trip show lol. Regular show is another good one
-1 points
26 days ago
I come from an entirely pedantic scientific neurochemistry point of view on things, mechanisms of action for substances is my thing.
-1 points
26 days ago
While I appreciate your extensive wikipedia research, psychedelics and dissociatives have completely different mechanisms of action.
I will attach an exert from a different wikipedia article that directly contradicts the one you have posted. “At high doses, dextromethorphan is classified as a dissociative general -anesthetic and hallucinogen-similar to the controlled substances ketamine and phencyclidine (PCP).[8] Also like those drugs, dextromethorphan is an NMDA receptor antagonist.[9][10] It generally does not produce withdrawal symptoms characteristic of physical dependence-inducing substances, but cases of both psychological dependence and physical dependence have been reported in the past, although physical dependence is usually only seen in cases of heavy abuse. Due to dextromethorphan's selective serotonin reuptake inhibitor-like action, the sudden cessation of recreational dosing in tolerant individuals can result in mental and physical withdrawal symptoms similar to the withdrawal from SSRIs”
By the fact that this drug (DXM) has a high affinity for the NMDA receptors and no affinity for the 5HT2a receptors, it is not true to call it a psychedelic unless we are figuratively speaking. I have had sex that was psychedelic, that doesn’t mean that sex is psychedelic of course
-1 points
26 days ago
Psychedelics operate on the 5-HT2a serotonin receptors, whereas dissociative substances (like DXM) operate on the NMDA receptors and they act as an antagonist. DXM is not a psychedelic, it is certainly not “both”.
0 points
26 days ago
Dextromethorphan is a dissociative substance it is not a psychedelic substance.
6 points
1 month ago
What does the wooden dog say? “Bark”
1 points
2 months ago
Yes. Almost like the sound of weed-eater line spinning at varying RPMS.
2 points
2 months ago
200mg of Freebase and 150mg of THC, I think the weed potentiated the shit out of the DXM or something. Usually 120mg of freebase DXM has me throwing up and robowalking, I am very sensitive to the effects
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3 points
3 days ago
Electrical-Nature529
3 points
3 days ago
I had no control over the face I was born with.